Department of Biotechnology

Biotechnology is an important tool that can be applied to various economic sectors of special interest to developing countries, such as the production of food crops, livestock management, human health care, chemical industry and environment management. The majority of developing countries including India lack the necessary qualified manpower to exploit such technologies.

Further, Biotechnology, as practiced today, requires inputs from not only one area of biological sciences, but requires a fusion of different modern biological and technological sciences. Biotechnology has become a multi-billion dollar industry all over the world.

Department of Biotechnology was established in 2001. The progress of the department is consistent over the years and presently holds many research projects funded by the UGC, DST, DBT and ICMR. During the last 10 years, the department has made all round progress and is on par with the well established departments of the KAHE. Scholars in the department are pursuing research in the areas of Nano-biotechnology, Food Technology, Fermentation Technology, Plant Tissue Culture, Animal Tissue Culture, Genetics and Molecular Biology, Microbial Technology and Phytochemistry. It is commendable to mention that the department is the proud recipient of Rs. 2.1 crores from the Govt. of India for various research and development programmes.

Programmes
  1. Under Graduate Programme
    • B.Sc. Biotechnology
  2. Post Graduate Programme
    • M.Sc. Biotechnology
  3. Research Programme
    • Ph.D. Biotechnology
Syllabus and Curriculum
Name Qualification Designation Email ID
Dr.R.Gopalan M.Sc, Ph.D. Professor gopalan.r@kahedu.edu.in
Dr.T.Sivaraman M.Sc., Ph.D. Professor thirunavukarasusivaraman@kahedu.edu.in
Dr.G.R.Prabu M.Sc, Ph.D. Associate Professor prabubiotech@kahedu.edu.in
Dr.A.Sangilimuthu M.Sc, M.Phil, Ph.D. Associate Professor sangilimuthu.a@kahedu.edu.in
Dr.P.Rajiv M.Sc., Ph.D. Assistant Professor rajiv.p@kahedu.edu.in
Dr.S.Barathkumar M.Sc., Ph.D Assistant Professor barathkumar.s@kahedu.edu.in
Dr.G.Archana M.Sc., Ph.D. Assistant Professor archana.g@kahedu.edu.in
Dr.C.Rajkuberan M.Sc., Ph.D. Assistant Professor rajkeberan.c@kahedu.edu.in
Dr.A.A.Arunkumar M.Sc., Ph.D Assistant Professor drarunkumar.aa@kahedu.edu.in
Dr.U.Ushani M.Sc., Ph.D. Assistant Professor ushani@kahedu.edu.in
Dr.P.K.Anilkumar M.Sc., Ph.D. Assistant Professor anilkumar.pk@kahedu.edu.in
S.Nishu M.Sc., (Ph.D) Assistant Professor nishu.s@kahedu.edu.in
Dr.J.Anburaj M.Sc., M.Phil., Ph.D Assistant Professor dranburaj.j@kahedu.edu.in
Dr.A.R.Sumayya M.Sc. M.Phil., Ph.D Assistant Professor sumayya.ar@kahedu.edu.in
Dr.R.S.Saranya M.Sc., Ph.D Assistant Professor saranya.rs@kahedu.edu.in

Infrastructure

  1. Staff room – 04
  2. Class room – 05

Laboratories

  1. UG & PG Biotechnology lab
  2. Plant Tissue culture lab
  3. Microbiology lab
  4. Animal Tissue culture lab
  5. R & D lab
  6. Animal house and Instrumentation lab
  7. Special purpose lab – Central Instrumentation Facility for analytical use

Major Equipment’s

Major Equipment’s

Inverted, Binocular and Trinocular Microscope, Deep Freezers, PCR, Real Time PCR, ELISA, AAS, UV-Visible Spectrophotometer, Gel documentation system, Southern Blotting Unit, Western Blotting Unit, Electrophoresis units, Walk-in Cold room, Walk-in Hot room, Cooling Centrifuge, Ultra Centrifuge, CO2 , BOD and Biological Incubators.

Department Library

  1. Total number of reference books: 102
  2. News letter : 15
  3. Journals : 15
  4. Proceedings : 21
  5. M.Phil and Ph.D theses : 27

Paper publications by the Faculty Members

Best Five Papers Faculty wise:

Dr. G.R. Prabu

  1. Amsalingam, R., Gajjeraman, P. and Sam, N. et al. 2017. Mechanism of Fenpropathrin Resistance in Red Spider Mite, Oligonychus coffeae (Acarina: Tetranychidae), Infesting Tea [Camellia sinensis L. (O. Kuntze)]. Appl. Biochem. Biotech. 181(2): 548–561. (Impact Factor: 1.751).
  2. Geethalakshmi, S., Barathkumar, S. and Prabu, G.R. 2015. The MYB transcription factor family genes in sugarcane (Saccharum sp). Plant Mol. Biol. Rep. 33(3): 512-531. (Impact Factor: 1.932).
  3. Anburaj, J., Viswanathan, C. and Prabu, G.R. 2014. Differential expression of microRNAs in dormant bud of tea [Camellia sinensis L. (O. Kuntze)]. Plant Cell Rep. 33(7): 1053-1069. (Impact Factor: 2.869).
  4. Viswanathan, C., Anburaj, J. and Prabu, G.R. 2014. Identification and validation of sugarcane streak mosaic virus encoded microRNAs and their targets in sugarcane. Plant Cell Rep. 33(2): 265-276. (Impact Factor: 2.869).
  5. Sakthivel, V., Rajendran, V., Rajesh, A., Karthikeyan, R., Kameshwaran, N., Anburaj, J., Viswanathan, C., Prabu, G.R., Fazil, Baksh, M., Gibbins, J.M. and Gail Hutchinson, E. 2013. Snakebite and its socio-economic impact on the rural population of Tamil Nadu, India. Plos One 8(11): e80090 (Impact Factor: 3.54).

Dr. A. Sangilimuthu

  1. Sangilimuthu, A. Yeggoni, D.P. Devadasu, E. and Subramanyam, R. 2017. Molecular binding mechanism of 5-hydroxy-1-methylpiperidin-2-one with human serum albumin. J. Biomol. Struct. Dyn. 1-8. (Impact Factor: 3.123)
  2. Kiran Chilivery, R. Sangilimuthu, A. and P Darsini, T. 2016. In Vitro Anti-Urolithiasis Potentials of Argemone mexicana L. Leaves. Current Clinical Pharma. 11(4): 286-290.
  3. Sangilimuthu, A. Ramalingam, S. Jebamalairaj, A. Subban, R. and Sundaram, K. M. 2016. Biochemical fingerprint and pharmacological applications of Barleria noctiflora Lf leaves. J. Complement Integr. Med. 13(4): 365-376.
  4. Sangilimuthu, A. Ramalingam, S. Jabamalai Raj, A. and Subban, R. 2015. Antihistamine from Tragia involucrata L. leaves. J. Complement Integr. Med. 12(3): 217-226.
  5. Sangilimuthu, A. Raj, A. J. and Sathishkumar, R. 2012. In vitro antioxidant activity of Barleria noctiflora L. f. Asian Pac. J. Trop. Biomed. 2(2): S716-S722.

Dr. P. Rajiv

  1. Rajiv, P. Rajeshwari, S. and Venckatesh, R. 2013. Vermiremediation: Detoxification of Parthenin toxin from Parthenium weeds. J. Hazard. Mater. 262: 489– 495. (Impact factor: 4.2).
  2. Rajiv, P. Rajeshwari, S. and Venckatesh, R. 2013. Fourier transform-infrared spectroscopy and Gas chromatography-mass spectroscopy: reliable techniques for analysis of Parthenium mediated vermicompost. Spectrochim. Acta Mol. Biomol. Spectrosc. 116: 642-645. (Impact factor: 2.09).
  3. Rajiv, P. Rajeshwari, S. and Venckatesh, R. 2013. Bio-Fabrication of zinc oxide nanoparticles using leaf extract of Parthenium hysterophorus L. and its size-dependent antifungal activity against plant fungal pathogens. Spectrochim. Acta Mol. Biomol. Spectrosc. 112: 384-387. (Impact factor: 2.09).
  4. Rajiv, P. Rajeshwari, S. and Venckatesh, R. 2014. Impact of Parthenium weeds on earthworms (Eudrilus eugeniae) during vermicomposting. Environ. Sci. Pollut. Res. 21: 12364-12371. (Impact factor: 2.6)
  5. Subhash Kumar, M. Rajiv, P., Rajeshwari, S. and Venckatesh, R. 2015. Spectroscopic analysis of vermicompost for determination of nutritional quality. Spectrochim. Acta Mol. Biomol. Spectrosc. 135: 252-255. (Impact factor: 2.09)

Dr. G. Archana

  1. Archana, G, Sabina, K, Babuskin, S, Radhakrishnan, K, Mohammed A Fayidh, AzhaguSaravanaBabu, P, Sivarajan, M and Sukumar, M 2013. Preparation and characterization of mucilage polysaccharide for biomedical applications. Carbohydrate Poly, 98:89–94 (Impact factor-3.4).
  2. Archana, G, Azhagu Saravana Babu, P, Sudharsan, K, Sabina, K, Palpandi Raja, R, Sivarajan, M. and Sukumar, M 2015. Evaluation of fat uptake of polysaccharide Coatings on deep-fat fried potato chips by confocal laser scanning microscopy (CLSM). Int. J. Food Prop, DOI: 10.1080/10942912.2015.1065426 (Impact factor-1.4).
  3. Radhakrishnan, K, Babuskin, S, AzhaguSaravanaBabu, P, Mohammed A Fayidh, Sabina, K, Archana, G, Sivarajan, M and Sukumar, M 2014. Bio protection and preservation of raw beef meat using pungent aromatic plants substances. J. Sci. Food Agri, 94:2456-2463 (Impact factor-1.759).
  4. Radhakrishnan, K, Sivarajan, M, Babuskin, S, Archana, G, Azhagu Saravana Babu, P and Sukumar, M. 2013. Kinetic modeling of spice extraction from S. Aromaticum and C. cassia. J. Food Engg. 117:, 326– 332 (Impact factor-2.3).
  5. Radhakrishnan, K, Babuskin, S, Azhagu Saravana Babu, P, Sasikala, M, Sabina, K, Archana, G, Sivarajan, M and Sukumar, M 2014. Antimicrobial and antioxidant effects of spice extracts on the shelf life extension of raw chicken meat. Int. J. Food Microbiol. 171: 32-40 (Impact factor-3.4).

Dr. C. Rajkuberan

  1. Sathishkumar, G. Logeshwaran, V. Sarathbabu, S. Jeyaraj, S.P. Rajkuberan, C. and S, Sivaramakrishnan. 2017. Green synthesis of magnetic Fe3O4 nanoparticles using Couroupita guianensis Aubl. fruit extract for their antibacterial and cytotoxicity activities. Artificial Cells, Nanomedicine and Biotechnology. Artif Cells Nanomed. Biotechnol. 2017 May 29:1-10. doi: 10.1080/21691401.2017.1332635. (Impact factor – 5.6) .
  2. Sathishkumar, G. Rajkuberan, C. Manikandan, K. Prabukumar, S. DanielJohn, J. and Sivaramakrishnan, S. 2016. Facile biosynthesis of antimicrobial zinc oxide (ZnO) nanoflakes using leaf extract of Couroupita guianensis Aubl. http://dx.doi.org/10.1016/j.matlet.2016.11.100. (Impact factor 2.7)
  3. Rajkuberan, C. Prabukumar, J. SathishKumar, G. and Sivaramakrishnan, S. 2016. Facile synthesis of silver nanoparticles using latex of Euphorbia antiquorum latex extract and evaluation of their biomedical perspectives as anticancer agents. Journal of Saudi Chemical Society doi:http://dx.doi.org/10.1016/j.jscs.2016.01.002. (Impact factor 1.9).
  4. Rajkuberan, C. Prabukumar, J. SathishKumar, G. Ravindran, K. Wilson, A. and Sivaramakrishnan, S. 2016. Formulation of Carica papaya latex-functionalized silver anoparticles for its improved antibacterial and anticancer applications. J.Mol.Liq. 219: 232-238. (Impact factor 2.7)
  5. Rajkuberan, C. Sudha, K. SathishKumar, G. and Sivaramakrishnan, S. 2015. Antibacterial and cytotoxicity of silver nanoparticles synthesized using latex of Calotropis gigantea. Spectrochimica Acta Part A. 136 (5): 924–930. (Impact factor 2.5).

Dr. U. Ushani

  1. Ushani, U. Rajesh Banu, J. Kavitha, S. Elango Mathavan, R. and Yeom, I.T. 2017. Immobilized and MgSO4 induced cost effective bacterial disintegration of waste activated sludge for effective anaerobic digestion, Chemosphere. 175: 66-75. (Impact Factor: 3.69)
  2. Ushani, U. Rajesh Banu, J. Tamilarasan, K. Kavitha, S. and Yeom, I.T. 2017. Surfactant coupled sonic pretreatment of waste activated sludge for energetically positive biogas generation, Biores. Technol. DOI:10.1016/j.biortech.2017.05.201. (Impact Factor 4.917)
  3. Rajesh Banu, J. Ushani, U. Rajkumar, M. Naresh Kumar, R. Parthiba Karthikeyane, O. 2017. Impact of mild alkali dosage on immobilized Exiguobacterium spp. mediated cost and energy efficient sludge disintegration. Biores. Technol. In press, DOI:10.1016/j.biortech.2017.08.216. (Impact Factor 4.917)
  4. Ushani, U. Kavtiha, S. Johnson, M. Yeom, I.T. and Rajesh Banu, J. 2016. Upgrading the hydrolytic potential of immobilized bacterial pretreatment for boosting biofuel production. Environ. Sci. Pollut. Res. 24: 813-826. (Impact Factor 2.760)
  5. Kavitha, S. Rajesh Banu, J. Subitha, G. Ushani, U. and Yeom, I.T. 2016. Impact of thermo-chemo-sonic pretreatment in solubilizing waste activated sludge for biogas production: Energetic analysis and economic assessment. Biores. Technol. 219: 479–486. (Impact Factor 4.917)

Dr. P.K. Anilkumar

  1. Anil Kumar, P. K. and Suresh P. V. 2014. Biodegradation of shrimp biowaste by marine Exiguobacterium sp.CFR26m and concomitant production of extracellular protease and antioxidant materials: production and process optimization by response surface methodology. Marine Biotech. 16: 202–218. (Impact Factor: 3.062)
  2. Suresh, P.V. and Anil Kumar, P.K. 2012. Enhanced degradation of a-chitin materials prepared from shrimp processing byproduct and production of N-acetyl-D-glucosamine by thermoactive chitinases from soil mesophilic fungi. Biodegrad. 23(4): 597-607. (Impact Factor: 2.208)
  3. Suresh, P.V, Anil Kumar, P.K. and Sachindra, N.M. 2011. Thermoactive β-N-acetylhexosaminidase production by a soil isolate of Penicillium monoverticillium CFR 2 under solid state fermentation: parameter optimization and application for N-acetyl chitooligosaccharides preparation from chitin. World J. Microbiol. Biotechnol. 27: 1435- 1447. (Impact Factor: 1.532).
  4. Reeta, D, Anil Kumar, P.K, Shamala, T.R. and Chandrashekar, A. 2008. Biosynthesis of polyhydroxy alkanoates copolymers in E. coli using genes from Pseudomonas and Bacillus. Antonie van Leeuwenhoek 94: 207–216. (Impact Factor: 1.944)
  5. Anil Kumar, P.K, Shamala, T.R, Kshama, L, Prakash, M.H, Joshi, G.J, Chandrashekar, A, Latha Kumari, K.S. and Divyashree, M.S. 2007. Bacterial synthesis of polyhydroxybutyrate-co-hydroxyvalearte using carbohydrate rich mahua (Madhuca sps) flowers: J. Appl. Microbiol. 103: 204-209. (Impact Factor: 2.156)

Dr. T. Sivaraman

  1. Biswajit Goraiand and Sivaraman, T. 2017. In silico screening of crucial residues for hemolytic activities of cardiotoxin 1 from Najanaja and in vitro validations.Int. J. Biol. Macromol. 95: 1022-1036. (Impact factor: 3.67)
  2. Sivakumar, D.Krishna Mohan Surapaneni, Prabhu, PC. Hari, N. Thiruvasagam, P. Rajasekaran, M. and Sivaraman, T. 2016. Evaluation of the anticancer properties of the predicted hBaxBH3-mimetic compound 2-hydroxy-3, 5-dinitrobenzamide in a mammary carcinogenesis-induced rat model. RSC Adv. 6: 2854-2869. (Impact factor: 3.11)
  3. Richa, T. and Sivaraman, T. 2014. OneG-Vali: A Computational Tool for Detecting, Estimating and Validating Cryptic Intermediates of Proteins under Native Conditions. RSC Adv. 4(68): 36325-36335. (Impact factor: 3.11)
  4. Biswajit Gorai. and Sivaraman, T. 2013. Unfolding stabilities of two paralogous proteins from Najanajanaja (Indian cobra) as probed by molecular dynamics simulations. Toxicon. 72: 11-22. (Impact factor: 1.93)
  5. Richa, T. and Sivaraman, T. 2012. OneG: A Computational Tool for Predicting Cryptic Intermediates in the Unfolding Kinetics of Proteins under Native Conditions. PLoS ONE. 7(3): 1-13, e32465. (Impact factor: 2.81)

Dr. A.A. Arunkumar

  1. Lokeswari, M and Arunkumar, AA. 2016. Effluent Treatment Emphasis on Spectroscopy. IJRSET, 3(5):1-6 (Impact Factor: 0.833).
  2. Arunkumar, AA, Sivaraman, T, and Manimekalan, A. 2017. Species Diversity and Habitat Inventory of Puntius sp. from Various Water Bodies of South India. J. Pharm. Sci. & Res. 9(10), 1775-1784 (Impact Factor: 0.391).

Dr. J. Anburaj

  1. Anburaj, J, Shengrui Liu, Xiao Zhang, Ran Zhang, Mingzhu Shangguan, Chaoling Wei. 2017. Genome-wide identification of microRNAs responsive to Ectropis oblique feeding in tea plant (Camellia sinensis L.). Scientific Reports. 7: 13634 (IF 4.259).
  2. Anburaj, J. Xiao Zhang, Yan Hou, Mingzhu Shangguan, Prabu Gajjeraman, Yeyun Li, Chaoling Wei. 2017. Genome-wide identification of conserved and novel microRNAs in one bud and two tender leaves of tea plant (Camellia sinensis) by small RNA sequencing, microarray-based hybridization and genome survey scaffold sequences. BMC Plant Biology. (IF 3.964)
  3. Ying-Hui Hou, Anburaj Jeyaraj, Xiao Zhang and Chao-Ling Wei. 2016. Absolute quantification of microRNAs in green tea (Camellia sinensis) by stem-loop quantitative real-time PCR. J Sci Food Agric. 97 (9): 2975-2981 (IF 2.463).
      • EventsNational Conference
        1. National Level Competition for Bio-Science Students Becon Fest, IIT-Delhi on July 5 -6, 2018.
        2. National Conference on “Plant Based Drugs – Biotechnological Implications” during 10 -11, August, 2017.
        3. National Conference on “Microbial Biotechnology for Sustainable Agriculture and Food Safety” during 27-28 July, 2017.

        Workshop

        1. Science Academics Lecture Workshop funded by INSA-IASC-NASC, Bengalore, New Delhi on June 27-28, 2018.
        2. Science Academies Lecture Workshop on “Recent advances in Biological Sciences” during 24 -25, July, 2017.

        Association Meet

        1. Department association Inauguration on July 2018.