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Department of Chemistry

Overview

The Department of Chemistry started functioning from the year 2004. It is specialized in five main areas of research namely Synthetic Organic Chemistry, Phytochemistry, Medicinal Chemistry, Bio-inorganic and Environmental Chemistry. During the last 10 years the Department has achieved remarkable progress in terms of research output.

Programme

Programmes
  1. Under Graduate Programme
    • B.Sc Chemistry
  2. Post Graduate Programme
    • M.Sc Chemistry
  3. Research Programme
    • Ph.D
Syllabus and Curriculum

Faculty

Name Qualification Designation Email ID
Dr.S.Ravi M.Sc., Ph.D. Professor ravi.s@kahedu.edu.in
Dr.A.Thangamani M.Sc., M.Phil., Ph.D. Associate Professor thangamani.a@kahedu.edu.in
Dr.M.R.Ezhilarasi M.Sc., M.Phil., Ph.D. Associate Professor ezhilarasi.mr@kahedu.edu.in
Dr.K.Sundaram M.Sc., Ph.D. Assistant Professor sundaram.k@kahedu.edu.in
Dr.M.Makeswari M.Sc., Ph.D. Assistant Professor makeswari.m@kahedu.edu.in
B.Prabha M.Sc., M.Phil. Assistant Professor prabha.b@kahedu.edu.in
R.Kumar M.Sc., M.Phil., Assistant Professor kumar.r@kahedu.edu.in
H.Revathi M.Sc., M.Phil., Assistant Professor revathi.h@kahedu.edu.in
Dr.M.Gopalakrishnan M.Sc., Ph.D Assistant Professor Gopalakrishnan.m@kahedu.edu.in
Dr.G.Ayyannan M.Sc., B.Ed., M.Phil., Ph.D Assistant Professor Ayyannan.g@kahedu.edu.in
K.Sathya M.Sc., M.Phil., (Ph.D) Assistant Professor k.sathiya@kahedu.edu.in
Dr.S.Manickasundaram M.Sc., M.Phil., (Ph.D) Assistant Professor manickasundaram.s@kahedu.edu.in
Dr.E.Karthikeyan M.Sc., Ph.D Assistant Professor karthikeyan.e@kahedu.edu.in

Infrastructure

Department infrastructure

  • Staff room – 5
  • Class room – 7

List of available labs

  • UG laboratory-3
  • PG laboratory-2
  • Research Laboratory-1
  • DST laboratory

Equipments available

  • Microwave oven (Manufacturer: M/s CEM Corporation; Germany Model: Discover Benchmate)
  • Rotary evaporator (Manufacturer: M/s Superfit continental Pvt. Ltd., India)

Library

  • Department library : 122 Books

Lab Photos

Publications

Paper publications by the Faculty Members

Best Five Papers Faculty wise:

Dr.S.Ravi

  1. Venkatareddy, G. and Ravi, S. 2017. Cinnamoylated chloroquine analogues: A new structural class of antimalarial agents. Eur. J. Med. Chem. 135: 382-391.( Impact factor 4.519)
  2. Ali Muhammad, S. Thangamani, A. and Ravi, S. 2016. Synthesis and evaluation of some novel N-substituted rhodanines for their anticancer activity, Med. Chem. Res. 25: 994-1004. (Impact factor 1.277)
  3. Kathirvel, P. and Ravi, S. 2012. Chemical composition of the essential oil from basil (Ocimumbasilicum Linn.) and its in vitro cytotoxicity against HeLa and HEp-2 human cancer cell lines and NIH 3T3 mouse embryonic fibroblasts. Nat. Prod. Res. 26:1112-1118. (Impact factor 1.828)
  4. Ravi, S. Chiruvella, K. K. Rajesh, K., Prabhu, V. and Raghavan, S.C. 2010. 5-Isopropylidene-3-ethyl rhodanine induce growth inhibition followed by apoptosis in leukemia cells. Eur. J. Med. Chem. 45:2748-2752. (Impact factor 4.519)
  5. Moorthy, B. T. Ravi, S., Srivastava, M. Chiruvella, K. K. Hemlal, H. Joy, O. and Raghavan, S. C. 2010. Novel rhodanine derivatives induce growth inhibition followed by apoptosis. Bioorg. Med. Chem. Lett. 20: 6297-6301. (Impact factor 2.42)

Mrs. R. Sharmila Devi

  1. Sharmila Devi, R., &Gayathri, R. (2014) Green Synthesis of Zinc Oxide Nanoparticles by Using Hibiscus rosa-sinensis. International Journal of Current Engineering and Technology, 4(4), 2444-2446.
  2. Sharmila Devi, R. Venckatesh, D. and Sivaraj, D. 2014. Synthesis of Titanium Dioxide Nanoparticles by Sol-Gel Technique. International Journal of Innovative Research in Science, Engineering and Technology. 03: 15206-15211. doi:10.15680/ijirset.2014.0308020
  3. Sharmila Devi, R., & Sebastian Antony Selvan, C. (2015) Green Synthesis of Silver Nanoparticles Loaded with Activated Carbon and its Characterization. International Journal of Research in Chemistry and Environment, 5(3), 24-27.
  4. Sharmila Devi, R and Sebastian Antony Selvan, C. 2017. Greener synthesis and characterization of silver nanoparticles using Murraya koenigii leaf extract and its antibacterial activity. International Journal of Pharma and Bio Sciences. 8: 292-298

Dr. A.Thangamani

  1. Ali Muhammad, S. Thangamani, A. and Ravi, S. 2017. Novel phenothiazine-based chalcone derivatives with various N-Substituted rhodanines induce growth inhibition followed by apoptosis in leukemia cells. Res. Chem. Intermed. DOI: 10.1007/s11164-017-2953-0. (Impact factor 1.369)
  2. Chandralekha, E. Thangamani, A. and Valliappan, R. 2013. Efficient atom-economical solvent-free one-pot multicomponent synthesis of 2-amino-4H-benzo[b]pyrans catalyzed by solid base SiO2-OK as a reusable catalyst. Res. Chem. Intermed. 41(4): 1951-1966. (Impact factor 1.369)
  3. Thangamani, A. 2010. Regiospecific synthesis and biological evaluation of spirooxindolopyrrolizidines via [3+2] cycloaddition of azomethine ylide. Eur. J. Med. Chem. 45(12): 6120-6126. (Impact factor 4.519)
  4. Chandralekha, E. Thangamani, A. and Valliappan, R. 2012. Ultrasound-promoted regioselective and stereoselective synthesis of novel spiroindanedionepyrrolizidines by multicomponent 1,3-dipolar cycloaddition of azomethine ylides. Res. Chem. Intermed. 39(3): 961-972. (Impact factor 1.369)
  5. Ali Muhammad, S Ravi, S. Thangamani, A. and Chandrasekaran. B. 2017. Synthesis, antiproliferative activity and docking study of novel rhodanine derivatives as Bcr-Abl T1351 inhibitors. Res. Chem. Intermed. DOI: 10.1007/s11164-017-2968-0. (Impact factor 1.369)

Dr. M.R Ezhilarasi

  1. Ezhilarasi, M. R. Prabha, B. and Santhi, T. 2015. Corrosive Inhibitive Effect of Pyrazole Compounds towards the Corrosion of Mild Steel in Acidic Medium. Rasayan. J. Chem. 8: 71-83. (Scopus)
  2. Ezhilarasi, M. R. Prabha, B. and Santhi, T. 2015. Pyrazole Methyl Substituted Compound used as a Corrosive Inhibitor for Mild Steel in Acidic Environment. Res. J. Chem. Sci. 5: 1-12.(Impact factor : 0.654)
  3. Ezhilarasi, M. R.and Prabha, B.2015. Comparative study of synthesis and Spectral Studies of Thiophene Carboxylate derivatives by Microwave Irradiation and Conventional Method. Chem. Sci. Trans. 4:967-974 .(Impact factor : 0.875)
  4. Ezhilarasi, M. R., Prabha, B., and Raja, C. 2016. A facile one pot Microwave Synthesis of 2-amino-5-aryl thiazole by using NaHSO4 –SiO2Heterogenous Catalyst in Dry Media. Res J. Pharm. Biol. Chem. Sci. 7: 205-210. (Impact factor 0.35)
  5. Raja, C. Ezhilarasi, M R. Prabha, B. And Kulandhaivel, M. 2017. Synthesis, Spectral Characterization and Antimicrobial Activities of Ethyl-2-(4-(naphthalene-1-yl)-6-phenylpyrimidin-2-yl amino) acetate Derivatives. Chem. Sci. Trans, 6(4), DOI:10.7598/cst2017.1403 .(Impact factor : 0.875)

Dr. K.Sundaram

  1. Sundaram, K., and Ravi, S. 2013. Microwave Assisted Synthesis of 3-α-carboxyEthylrhodanine Derivatives and there in vitroAntibacterial Activity. J. Appl. Pharm. Sci. 3: 133-135. (Impact factor 0.524)
  2. Sundaram, K. and Ravi, S. 2013. Synthesis of 5-benzylidine-3-a-carboxy Ethyl Rhodanines and Study of Their Anticancer Activity against HeLa Cell Lines and Antibacterial Activity against MRSA. Asian J. Chem. 25: 10353-10356. (Impact factor 0.145).
  3. Celestina, S . Sundaram, K. and Ravi, S. 2015. Synthesis of 5-benzylidine Rhodanines and their Cytotoxicity on HeLa Cell Lines. Res. J. Pharm., Biol. Chem. Sci., 6: 1695-1700. (Impact factor 0.145)
  4. Sundaram, K. and Ravi, S. 2013. Synthesis, antibacterial activity against MRSA, and in vitro cytotoxic activity against HeLa cell lines of novel 3-α-carboxy ethyl-5-benzylidene rhodanine derivatives. Res. Chem. Intermed. 41:1011-1021. doi:10.1007/s11164-013-1251-8 (Impact factor 1.369)
  5. Suresh, E. Sundaram, K. Kavitha, B. and Senthil Kumar, N. 2016. Square wave voltammeter sensing of ibuprofen on glassy carbon electrode. Int. J. Pharm.Tech. Res. 9: 182-188. (Impact factor 0.93)

Dr. M. Makeswari

  1. Makeswari, M. and Santhi, T. 2013. Optimization of Preparation of Activated Carbon fromRicinuscommunisLeaves by Microwave-Assisted Zinc Chloride Chemical Activation: Competitive Adsorption of Ni2 Ions from Aqueous Solution. J. Chem., 2013, 1-12. doi:10.1155/2013/314790 (Impact factor 1.419)
  2. Makeswari, M. and Santhi, T. 2013. Removal of Malachite Green Dye from Aqueous Solutions onto Microwave Assisted Zinc Chloride Chemical Activated Epicarp of Ricinuscommunis. J. Water Resource and Protection, 05: 222-238. doi:10.4236/jwarp. 2013.52023 (Impact factor 0.95)
  3. Makeswari, M. and Santhi, T. 2014. Adsorption of Cr(VI) from Aqueous Solutions by Using Activated Carbons Prepared from RicinusCommunis Leaves: Binary and Ternary systems. Arabian Journal of Chemistry, Doi:10.1016/j.arabjc.2013.10.005. (Impact factor 4.553)
  4. Makeswari, M. Santhi, T. and Manonmani. S. 2014. Adsorption of Cr(VI) ions from Aqueous Solutions onto Tannin Gel Prepared from Leaves of Ricinuscommunis. Int. J. Res. Chem. Environ., 4: 90-100.
  5. Makeswari, M., and Santhi, T. 2013. Use of Ricinuscommunis leaves as a low-cost adsorbent for removal of Cu (II) ions from aqueous solution. Res. Chem. Intermed, 40: 1157-1177. doi:10.1007/s11164-013-1029-z (Impact factor 1.369)

Ms. B.Prabha

  1. Ezhilarasi, M. R., Prabha, B.,&Santhi, T. (2015) Corrosive Inhibitive Effect of Pyrazole Compounds towards the Corrosion of Mild Steel in Acidic Medium. Rasayan Journal of Chemistry, 8(1), 71-83.
  2. Ezhilarasi, M. R., Prabha, B., & Santhi, T. (2015) Pyrazole Methyl Substituted Compound used as a Corrosive Inhibitor for Mild Steel in Acidic Environment. Research Journal of Chemical Sciences, 5(5), 1-12
  3. Ezhilarasi, M. R., Prabha, B.,&Kulandhaivel, M. (2015)Green Synthesis, Spectral Characterization And Biological Activity Of Novel Acetyl Pyrazole Derivatives, European Journal Of Pharmaceutical And Medical Research, 2(3),355-369
  4. Ezhilarasi, M. R.,&Prabha, B. (2015) Comparative Study of Synthesis and Spectral Studies of Thiophenyl Carboxylate Derivatives by Microwave Irradiation and Conventional Method, Chemical science transaction, 4(4), 967-974.
  5. Ezhilarasi, M. R., Prabha, B., &Raja, C. (2016) A facile one pot Microwave Synthesis of 2-amino-5-aryl thiazole by using NaHSO4 –SiO2Heterogenous Catalyst In Dry Media. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 7, 205-210.

Dr.M.Gopalakrishnan

  1. Gopalakrishnan, M. Shanmugan, S. and Palanisami, N. 2016. Synthesis and Spectroscopic Characterization of Tris(tert-butoxy)siloxy Titanium and Hafnium Complexes: Molecular Precursor to [M/Si/O (M =Ti, Hf)] Materials, Phosphorus Sulfur Silicon Relat. Elem. 192: 977-983 (Impact factor 0.809).
  2. Gopalakrishnan, M., Thirumoorthy, K. Bhuvanesh, N.S.P. and Palanisami, N. 2016. Eight Membered Cyclic-Borasiloxanes: Synthesis, Structural, Photophysical, Ring Strain and DFT calculations, RSC Advances, 6: 55698-55709. (Impact factor 3.108)
  3. Gopalakrishnan M and Palanisami, N. 2016. New sterically hindered tin(IV) siloxane precursors to tinsilicate materials: Synthesis, spectral, structural and photocatalytic Studies, RSC Advances, 6: 1760-1768. (Impact factor 3.108)
  4. Gopalakrishnan, M., Senthilkumar, K. Priya, R. R. Siva, R. and Palanisami, N. 2014. Synthesis, crystal structure, DNA binding and molecular docking studies on new copper(II) salicylate [Cu(DTBSA)2(2,2′-Bpy)](dmf), Inorg. Chem. Comm., 46: 54–59. (Impact factor 1.640).
  5. Hridya H, Amirta, A. Sankari, M. Gopalakrishnan, M. Thirumal Kumar, D. Priya doss, C.G. and Siva, R. 2015. Unraveling the inhibition mechanism of cyanidin-3-sophoroside on polyphenol oxidase and its effect on enzymatic browning of apples, Food Chem., 227: 102–110. (Impact factor 4.529).

Mr.R.Kumar

  1. Harshitharaj, P. K. Kumar, R. and Ravi, S. 2016. Synthesis, cytotoxic activity and molecular docking study of bis-rhodanine derivative. Journal of Chemical and Pharmaceutical Sciences, 9: 2478-2482 (Impact factor 0.20)
  2. Kanimozhi, K. Ali Muhammad, K.S. Kumar, R. and Ravi, S. 2016. Synthesis and molecular docking studies of novel phenothiazine chalcone derivatives as T315I mutated Bcr-Abl kinase inhibitors. Journal of Chemical and Pharmaceutical Sciences, 9: 1139-1143 (Impact factor 0.20)

Ms.H.Revathi

  1. H.Revathi, T.Murugan and R.Sharmila Devi, (2017). Removal of auromine-O dye from dye wastewater by adsorption using seeds of Annona reticulate. International Journal of Current Engineering and Technology, 7(3) : 958-961.

Mr.J.Balaji

  1. J.Balaji and M.G.Sethuraman, Corrosion Protection of Copper with 3-Glycidoxypropyltrimethoxysilane based Coating through 3-Amino- 5-Mercapto- 1,2,4-Triazole Doping, Research on Chemical Intermediates 42(2), (2016), 1315-1328.
  2. J.Balaji and M.G.Sethuraman, Studies on the effects of thiourea and its derivatives doped – hybrid/zirconium nanocomposite based sol-gel coating for the corrosion behaviour of aluminum metal, Progress in Organic Coatings, 99, (2016), 463-473.
  3. J.Balaji and M.G.Sethuraman, Improved corrosion resistance by forming multilayer over copper surface by electrodeposition followed by novel sol-gel coating method, RSC Advances, 6, (2016), 95396-95404.
  4. J.Balaji and M.G.Sethuraman, Study of ethylurea doped hybrid zirconia nanoparticles based sol-gel coating for corrosion protection of Aluminum, Materials Focus (American Scientific Publishers), 5, (2016), 368-376.
  5. J.Balaji and M.G.Sethuraman, Chitosan-doped- hybrid/TiO2 nanocomposite based sol-gel coating for the corrosion resistance of aluminum metal in 3.5% NaCl medium, International Journal of Biological and Macromaolecules, (2017), DOI: 10.1016/j.ijbiomac.2017.03.115

Mr.G.Ayyanan

  1. Chemical and electrochemical investigations of high carbon steel corrosion inhibition in 10 % HCl medium by quinoline chalcones.G. Ayyannan, K. Karthikeyan, S.Vivekananthan, M. Gopiraman, A. Rathinavelu, Ionics, 19 (2013) 919-932.
  2. New palladium(II) hydrazone complexes: Synthesis, structure and biological evaluation.G. Ayyannan, M. Mohanraj, G. Raja, N. Bhuvanesh, R. Nandhakumar, and C. Jayabalakrishnan, Journal of Photochemistry & Photobiology, B: Biology, 163 (2016) 1-13.
  3. Design, synthesis, structure and biological evaluation of new palladium(II) hydrazone complexes. G. Ayyannan, M. Mohanraj, G. Raja, N. Bhuvanesh, R. Nandhakumar, and C. Jayabalakrishnan, Inorganica Chimica Acta, 453 (2016) 562–573.
  4. Biological evaluation of organometallic palladium(II) complexes containing 4‐hydroxybenzoic acid (3‐ethoxy‐2‐hydroxybenzylidene)hydrazide: Synthesis, structure, DNA/protein binding, antioxidant activity and cytotoxicity. G. Ayyannan, M. Mohanraj, G. Raja, A. Manimaran, M. Velusamy, N. Bhuvanesh, R. Nandhakumar and C. Jayabalakrishnan, Applied Organometallic Chemistry, 31 (2017) 3599
  5. Evaluation of DNA binding, DNA cleavage, protein binding, radical scavenging and in vitro cytotoxic activities of ruthenium(II) complexes containing 2,4-dihydroxy benzylidene ligands. M. Mohanraj, G. Ayyannan, G. Raja and C. Jayabalakrishnan, Materials Science and Engineering C, 69 (2016) 1297–1306.

Events

  • EventsNational Conference
    1. National Conference on “Drug discovery from Medicinal and aromatic plants” (DDMAP-2017) on 2nd and 3rd of February 2017.
    2. National conference on ‘Advances in Environmental, Synthetic and Medicinal Chemistry” 5th and 6th of April 2016.
    3. National Conference on Recent Trends in Green and Medicinal Chemistry on 11-03-2015.
    4. National Conference on “Recent trends in Green chemistry, Medicinal chemistry and drug design” December 2017.

    Workshop

    1. Workshop Programme entitled “Interpretation of Spectral data and identification of phytoconstituents” on 1st and 2nd of September 2017.
    2. Workshop on “How to reduce the expenditure drastically in chemistry practicals” on 19th September 2016.
    3. Workshop Programme entitled “Interpretation of Spectral data and identification of phytoconstituents” on 10th & 11th March 2016
    4. Workshop on “Interpretation of Spectral data and identification of phytoconstituents” on 29-01-2015 & 30-01- 2015.
    5. Workshop Programme on “Radiochemistry”in which the resource persons are from Indian Association of Nuclear Chemists and Allied Scientists (IANCAS)- Indira Gandhi Centre for Atomic Research(IGCAR), Kalpakkam on 17th and 18th of November 2017.

    Hands on Training / Activities

    1. International “water Day” on 22nd March 2017.
    2. Hand’s on training Programme on “Spectroscopic and chromatographic techniques” on 21st September 2016 & 22nd December 2016.
    3. Hands on training programme on “Spectroscopic and chromatographic techniques” on 9th February 2016.
    4. Training programme on water analysis, November 2017.
    5. Hands on training programme in UV, FT-IR Spectrophotometers and Gas Chromatography instruments January 2018.
    6. National Seminar on “Environmental Chemistry” February 2018.

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